Introduction
Alzheimer-Associated Neuronal Thread Protein Assay Kit (Rare Earth-Sensitized Magnetic Particle Chemiluminescence)
Clinical significance
This kit is intended for the quantitative in vitro detection of Alzheimer-associated neuronal thread protein (AD7C-NTP) in human urine samples. It is clinically used as an aid in the diagnosis of Alzheimer's disease.
AD7C-NTP is a neuronal thread protein produced by neuronal cell bodies, expressed in neurons, and localized to axons of neuronal origin. Its levels are elevated in both cerebrospinal fluid (CSF) and urine of patients with Alzheimer's disease (AD), and its concentration is positively correlated with the severity of cognitive impairment. This feature makes it an important biomarker for the early diagnosis of AD.
Product detail
Applicable Departments: Neurology, Geriatrics, Memory Disorders Clinic, and Neuropsychology.
Performance Verification:
Product Advantages:
High sensitivity: ≤0.2 ng/mL
Wide linear range: 0.2–10 ng/mL
Rapid detection time: 20 minutes
Performance Parameters:
Sample Type: Urine
Precision: CV ≤ 8%
Reference Value: <1.5 ng/mL
Comparison Study: Correlation with the Yipu Nokang chemiluminescence assay showed an R² of 0.9936.
Clinical Applications:
Adjunctive diagnosis of Alzheimer's disease
Differentiation of dementia types
Risk screening for cognitive impairment
Monitoring of disease progression
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